Studies support the existence of a
critical time early in infancy during which the genetically predisposed atopic
infant is at higher risk for developing allergic sensitization. Thus, dietary
interventions in the first years of life have been analyzed for their effects
on the prevalence of allergic disease including food allergy. Both American and
European allergy expert committee guidelines recommend that solid foods be
introduced between four to six months of age in all infants. Other
organizations have also concluded that complementary foods may be safely
introduced between four and six months of age, although many still recommend or
prefer exclusive breastfeeding for the first six months of life. Recommendations
regarding when to introduce highly allergenic foods, particularly in high-risk
infants, have shifted over time.
While any food has the potential to
cause allergy, certain foods are more common triggers of significant acute
allergic reactions due to various factors. The most common food allergens in
children in the United States and many other countries include cow's milk (CM),
hen's egg, soy, wheat, peanut, tree nuts, and seafood. The American Academy of Pediatrics (AAP) had previously
suggested in 2000 that the introduction of certain highly allergenic foods be
delayed further in high-risk children: cow's milk (CM) until age one year; eggs
until age two years; and peanuts, tree nuts, and fish until age three years.
This recommendation was based upon early studies that suggested that delayed
introduction of solid foods might help prevent some allergic diseases, particularly
atopic dermatitis.
The most prevalent allergic or atopic disorders include
atopic dermatitis (AD), asthma, Allergic
Rhinitis (AR), and food allergies. These
conditions afflict 20 percent of the population of the United States, and their
prevalence appears to be increasing in developed nations. The increase in
atopic diseases has been recognized as a pandemic, thus emphasizing the need
for effective allergy prevention.
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